• EMBLEM PI’s (Drs. Sam Mbulaiteye, Esther Kawira, and Martin Ogwang) participate in the Burkitt Lymphoma Workshop held in Philadelphia.

    EMBLEM PI’s (Drs. Sam Mbulaiteye, Esther Kawira, and Martin Ogwang) participate in the Burkitt Lymphoma Workshop held in Philadelphia.

  • EMBLEM staff learn how to use “DataFax” forms, St. Mary’s Hospital, Lacor.

    EMBLEM staff learn how to use “DataFax” forms, St. Mary’s Hospital, Lacor

  • Site visit to Kuluva Hospital staff with Dr. Allan Hildesheim, IIB chief, Dr. Patrick Kerchan, co-PI, and Dr. Sam Mbulaiteye, PI.

    Site visit to Kuluva Hospital staff with Dr. Allan Hildesheim, IIB chief, Dr. Patrick Kerchan, co-PI, and Dr. Sam Mbulaiteye, PI.

  • Ronnie Ogwang and Charles Lsabirye present their concept for EMBLEM poster and tutorial to EMBLEM and Lacor staff.

    Ronnie Ogwang and Charles Lsabirye present their concept for EMBLEM poster and tutorial to EMBLEM and Lacor staff.

  • Jolly Steve, a BL patient successfully treated, shares a moment of joy with his doctors at Homabay, Kenya.

    Jolly Steve, a BL patient successfully treated, shares a moment of joy with his doctors at Homabay, Kenya.

  • EMBLEM Kenya team attending training in SOPs at Lacor Hospital

    EMBLEM Kenya team attending training in SOPs at Lacor Hospital.

  • EMBLEM PIs and staff launch field work at Homabay District Hospital, Kenya

    EMBLEM PIs and staff launch field work at Homabay District Hospital, Kenya

  • Dr. Esther Kawira, co-PI, with a BL patient who responded well in Shirati, Tanzania.

    Dr. Esther Kawira, co-PI, with a BL patient who responded well in Shirati, Tanzania.

  • EMBLEM BL clinic, laboratory, and office at Shirati, Tanzania.

    EMBLEM BL clinic, laboratory, and office at Shirati, Tanzania.

  • EMBLEM Community Advsiory Board in Tanzania touring the EMBLEM office (Dr. Changalucha, Father Aloys , Dr. Makwami) at Bugando Medical Centre.

    EMBLEM Community Advsiory Board in Tanzania touring the EMBLEM office (Dr. Changalucha, Father Aloys , Dr. Makwami) at Bugando Medical Centre.

The National Cancer Institute (NCI) is conducting a multicountry and multiyear case-control study of childhood Burkitt’s lymphoma in Uganda, Tanzania and Kenya. The study, entitled Epidemiology of Burkitt’s Lymphoma in East-African Children and Minors (EMBLEM), will evaluate the role of:

  1. Repeated malaria infections in endemic Burkitt’s lymphoma,
  2. Malaria genetic variants in Burkitt’s lymphoma,
  3. Epstein-Barr virus (EBV) genetic variants in Burkitt’s lymphoma.

The specific hypotheses that will be tested are, whether:

  • Carriage of genetic markers that increase resistance to malaria is associated with decreased risk of Burkitt’s lymphoma.
  • Certain EBV genetic variants are associated with increased risk for Burkitt’s lymphoma.

In addition, the study will generate a unique data and sample repository to allow for novel study exploration into the etiology and biology of the disease, including the use of genome-wide scans.

To learn more about EMBLEM and Burkitt lymphoma, watch our video.