Genetic Studies

The genetic studies utilize a variety of tools to answer specific questions that cannot be answered well using questionnaire or serological methods. These studies take advantage of high-throughput scanning for genome-wide association studies (GWAS) and whole or exome sequencing of tumor and germline genomes to study deeper aspects of endemic Burkitt Lymphoma (eBL) biology.

These studies are complex and involve collaboration with scientists from diverse disciplines. They provide exciting opportunities to bridge genetic, epigenetic, viral, immunological, and epidemiologic approaches to investigate the etiology of BL.

These studies fall into two broad categories:

  1. tumor-based studies, and
  2. germline studies.